On a Specific Enzym Which Decomposes Group A Substances

AN AEROBIC SOIL MICROORGANISM WHICH DECOMPOSES BLOOD GROUP SUBSTANCES II. : Effect of Cell-Free Extracts on Blood Group Substances.

Cell-free extracts of a number of microorganisms have been shown to possess enzymatic activity against blood group substances. Thus, enzymes of Bacillus fulminans, isolated by Iseki and Tsunoda (1952), were found to attack O(H) but not A or B substances. Extracts from strains of Lactobacillus bifidus, var. penn, have been shown (Springer et al., 1954; Gyorgy et al., 1954) to break down A, B, an...

On Group Specific a Substances

A method of preparation and a preliminary chemical investigation of the substance present in commercial (pig) pepsin which reacts with human A antiserum are presented. The material offers especial advantage in securing in quantity a serologically highly active preparation suitable for further studies. Active preparations were isolated moreover from commercial (pig) gastric mucin. Some other mat...

An aerobic soil microorganism which decomposes blood group substances. I. Metabolic and immunochemical studies.

A number of microorganisms have the ability to degrade cellulose, agar, bacterial polysaccharides, and blood group substances. The Myxococcus of Morgan and Thaysen (1933) was shown to split blood group A substance in horse saliva but not the A substance in peptone (Landsteiner and Chase, 1935a, b). It also attacked the specific polysaccharide of Shigella dysenteriae (Shiga and Flexner), pneumoc...

A Microorganism Decomposing Group-Specific A Substances.

The use of bacteria to effect the degradation of serologically active carbohydrates was initiated by Avery and Dubos (1930; see also Dubos and Avery 1931) in studies on the capsular carbohydrate of Pneumococcus Type III; and other microorganisms capable of splitting polysaccharides of bacterial origin have since been found. The present report concerns the isolation and cultural characters of an...

A ferrichrome-requiring Arthrobacter which decomposes puromycin aminonucleoside.